SPRAVATO™ is taken with a daily oral antidepressant
You administer SPRAVATO™ nasal spray yourself under the supervision of a healthcare professional at a certified SPRAVATO™ treatment center
SPRAVATO™ is taken twice a week for the first four weeks
After the first four weeks, SPRAVATO™ is taken once a week for a month
After this, SPRAVATO™ is usually taken either once a week or once every two weeks
The nasal spray medication used in SPRAVATO™ is covered by every major insurance provider. However, Ketamine is an off-label treatment. Therefore, the appointment for SPRAVATO™ is not covered in-network while the medicine SPRAVATO™ used in the appointment is covered. Please call our office to learn more.
Before you take SPRAVATO™, talk to your doctor about your full medical and depression treatment history, including if you have a history of abusing prescription or street drugs or a problem with alcohol.
Ketamine is given in small doses for the treatment of depression. As such, a typical side effect is mild sedation. Some patients complain of mild nausea, which is easily treated with anti-anxiety medication. Some patients have mild elevations or reductions in blood pressure.
The most common side effects that can occur during and after taking SPRAVATO® include:
If these common side effects occur, they usually happen right after taking SPRAVATO® and go away the same day.
Because of the possibility of nausea and vomiting, you should avoid eating two hours before, and drinking liquids 30 minutes before, taking SPRAVATO®.
No, administered at small doses in a medical setting, there is no evidence that Spravato is addictive. In contrast, those who abuse ketamine recreationally do so at very high doses to induce psycho-active affects.
Yes, clinical experience supports that Spravato can be effective for patients with treatment resistant depression, including those who have already tried ECT and TMS without benefit.
You’ll take SPRAVATO® twice a week for the first month. During the second month, you’ll take it once a week. After that, you’ll take it once a week or once every two weeks. You will continue to take your oral antidepressant as prescribed.
In clinical studies, improvement of depressive symptoms was demonstrated at four weeks by SPRAVATO® plus an oral antidepressant, compared with placebo nasal spray plus an oral antidepressant. Not all patients will respond to SPRAVATO®.
Some patients taking SPRAVATO® may experience nausea or vomiting. Because of this, you should avoid eating two hours before, and drinking liquids 30 minutes before, taking SPRAVATO®.